University of Minnesota
School of Physics & Astronomy

Biophysics Seminar

Tuesday, April 7th 2015
2:30 pm:
Biophysics Seminar in 110 PAN
Speaker: Jasmine Foo, School of Mathematics, University of Minnesota
Subject: Evolutionary dynamics in spatially structured populations

In this talk I will present results on a model of spatial evolution on a lattice, motivated by the process of carcinogenesis from healthy epithelial tissue. Cancer often arises through a sequence of genetic alterations. Each of these alterations may confer a fitness advantage to the cell, resulting in a clonal expansion. To model this we will consider a generalization of the biased voter process which incorporates successive mutations modulating fitness, which is interpreted as the bias in the classical process. Under this model we will investigate questions regarding the rate of spread and accumulation of mutations, and study the dynamics of spatial heterogeneity in these evolving populations.

The weekly calendar is also available via subscription to the physics-announce mailing list, and by RSS feed.